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Research and Publications
One of our main objectives is to analyze the impacts effects of environmental exposures on human health. In the context of environmental health, the recognition, acknowledging that exposures can induce mutations in DNA represents a fundamental milestone for assessing risks and preventing potential harm. Consequently, we have categorized chemical agents based on their ability capacity to alter the DNA sequence. This information plays a crucial role in determining environmental risks and shaping current regulations to reduce exposure. However, recent discoveries suggest that the molecular impact of the environment may extend well beyond interaction with DNA sequence.
These sections describe the main molecular mechanisms on which we have focused our research.
The field of Epigenetics encompasses various mechanisms, including DNA methylation, histone modification, and microRNA. DNA methylation is a covalent, heritable modification in somatic cells after cell division. 5-methyl-cytosine (5MeC) represents...
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Extracellular vesicles (EVs) are spherical structures delimited by a double lipid layer that can be generated by cells and secreted into the extracellular space. There are various types classes of...
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Telomeres are repetitive sequences of nucleotides (TTAGGG), which, along with specialized proteins, form a cap at the ends of chromosomes. They have various functions in preserving chromosome stability, protecting them...
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Mitochondria play the dual role of are the main intracellular source of energy and primary target of reactive oxygen species (ROS), which are generated as natural byproducts of aerobic metabolism...
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